Note: The job is a remote job and is open to candidates in USA. Madrigal Pharmaceuticals is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH). The Senior Director, Legal and Compliance Operations, is responsible for supporting the execution and continuous improvement of Madrigal’s Compliance Program, focusing on project management, policy governance, and operational excellence across the Legal and Compliance function.

Responsibilities

• Partner with Compliance and Legal team members to maintain and enhance infrastructure that supports a culture of compliance and shared accountability across the organization
• Project management tied to legal and compliance operational excellence with sub-functions - creating metrics /key performance indicators/dashboards, etc
• Collaborate cross-functionally to identify policy and guidance needs; develop and refine policies, procedures, and supporting documentation to ensure clarity and usability
• Lead the design, implementation, and continuous improvement of risk-based compliance training programs tailored to functional audiences
• Support the annual compliance risk assessment process, including data gathering, analysis, and identification of areas for program enhancement
• Provide practical compliance guidance to business stakeholders and support the integration of compliance controls into existing business processes
• Drive continuous improvement initiatives, including documentation, tracking, and reporting of compliance activities and program effectiveness
• Maintain current knowledge of applicable laws, regulations, and industry guidance, including federal and state pricing regulations, privacy laws, OIG and DOJ guidance, the PhRMA Code, and state marketing compliance requirements
• Lead and execute high-impact legal and compliance projects and cross-functional initiatives as assigned by the Chief Legal Officer or Global Compliance Officer

Skills

• Bachelor's degree required; advanced degree (JD, MBA, or Master's) strongly preferred
• 12–15+ years of progressive experience in pharmaceutical or biotech compliance, legal, or related functions
• Demonstrated success in implementing policy governance frameworks and compliance training programs
• Strong leadership capability, organizational awareness, sound judgment, and business acumen, with the ability to make informed decisions in collaboration with stakeholders
• Excellent interpersonal, written, and presentation skills
• Proven ability to operate effectively in a fast-paced, high-growth environment while maintaining a focus on quality, ethics, and collaboration
• Knowledge of laws, regulations, and industry guidance relevant to the pharmaceutical industry
• Strong collaboration skills and ability to work effectively across cross-functional teams
• Strong problem-solving and risk assessment capabilities
• Ability to prioritize and manage multiple complex and confidential initiatives simultaneously
• Advanced degree (JD, MBA, or Master's) strongly preferred

Benefits

• Equity offers meaningful opportunity allowing our employees to share in the success they help create
• All full-time employees receive equity, which we believe reinforces our ownership culture
• Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans
• Additional voluntary benefits like supplemental life insurance, legal services, and other offerings
• Mental health benefits through our Employee Assistance Program for employees and their family
• Other benefits in accordance with applicable federal, state, and local laws
• Reasonable accommodations for individuals with disabilities throughout the hiring process

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