Note: The job is a remote job and is open to candidates in USA. Alnylam Pharmaceuticals is the leader in RNAi therapeutics, dedicated to transforming the lives of people with rare and common diseases. They are seeking a highly skilled Senior Associate Scientist, Pharmacometrics to optimize, automate, and scale data workflows supporting drug development.

Responsibilities

• Streamline data cleaning, transformation, and QC processes to improve reproducibility, traceability, and robustness of analytical workflows
• Design, develop, and maintain reusable, well-documented code, libraries, and utilities in R and/or Python to support scientific analyses
• Create interactive tools or dashboards to support internal users (e.g., Shiny, Dash)
• Apply software engineering best practices (version control, testing, modular design)
• Communicate user needs with the vendor
• Collaborate with IT and the vendor to support change controls
• Work closely with pharmacometricians to support PK/PD and exposure–response analyses
• Learn foundational PK/PD and modeling concepts on the job
• Translate scientific requirements into robust computational solutions
• Enable faster iteration and insight generation for modeling and simulation activities
• Partner with Clinical Pharmacology, Statistics, and related quantitative groups
• Support data standards, organization, and metadata practices
• Communicate technical solutions clearly to both technical and non-technical colleagues

Skills

• MS in Data Science, Computer Science, Statistics, Applied Mathematics, Engineering, or related quantitative field
• Strong programming background in R and/or Python
• Demonstrated experience optimizing, automating, or scaling data analysis workflows
• Experience working with complex scientific or real-world datasets
• Solid understanding of data structures, algorithms, and analytical best practices
• Exposure to regulated environments and audit-ready workflows
• Strong problem-solving skills and curiosity
• Prior exposure to pharmacometrics, biomedical data, or clinical data would be a plus

Benefits

• Annual short-term incentive award (e.g., bonus or sales incentive)
• Annual long-term incentive award (e.g., equity)
• Medical, dental, and vision coverage
• Life and disability insurance
• A lifestyle reimbursement program
• Flexible spending and health savings accounts
• 401(k)with a generous company match
• Paid time off
• Wellness days
• Holidays
• Two company-wide recharge breaks
• Generous family resources and leave

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