Work Flexibility: Remote Stryker is seeking a Principal Clinical Study Manager to join our Neurovascular Division. This is a remote position based anywhere within the United States. As the Principal Clinical Study Manager, you will lead the planning and execution of complex clinical studies that advance innovation in stroke care. You will collaborate with cross-functional teams, ensure compliance with regulatory standards, and drive operational excellence to deliver high-quality results. What You Need Lead cross-functional clinical project teams, setting study strategy, timelines, budgets, and performance expectations across multiple global trials. Design and develop clinical study protocols and investigational plans in collaboration with physician advisors and internal stakeholders. Ensure compliant execution of clinical studies aligned with IRB/EC requirements, global regulatory standards, and company policies. Own end-to-end study management, including budget development, cost control, and delivery of high-quality, ethical, and publishable results. Oversee site selection, qualification, monitoring, and close-out, while directing CRAs and resolving operational and site-level issues. Drive study start-up and execution activities, including contracts, site training, CRF design, data management coordination, and CRO oversight. Monitor study performance through metrics and reporting, implementing corrective actions and maintaining clear communication with sites and stakeholders. Support regulatory submissions (e.g., IDEs, amendments) and lead study reporting, from progress updates through final reports and publication. Required Bachelor's degree in science or health care related field 8+ years of relevant work experience in clinical research with minimum 4 years of clinical study management experience Experience in the Medical Device or Pharmaceutical industry Proven ability to manage complex study programs, budgets, schedules, and cross-functional teams Strong leadership, communication, and stakeholder management skills Preferred CCRP, ACRP, PMP, PgMP, or equivalent professional certification Experience leading cross-functional teams Posting Date: 06/02/2026 United States of America Pay Ranges: USN: $118,000 - $196,700 USD Annual US5: $123,900 - $206,500 USD Annual US10: $129,800 - $216,400 USD Annual US15: $135,700 - $226,200 USD Annual US20: $141,600 - $236,000 USD Annual US30: $153,400 - $255,700 USD Annual View the U.S. work location and transparency guide to find the pay range for your location. Travel Percentage: 30% Stryker Corporation is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, or protected veteran status. Stryker is an EO employer – M/F/Veteran/Disability. Stryker Corporation will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information.